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PSC Research Explained

Summaries of PSC research

PSC Research Explained by PSC Support

Stay informed with PSC Research Explained. We translate the latest clinical trials and scientific breakthroughs into clear, plain English summaries for patients:

Epstein-Barr Virus and PSC

05 Feb 2026

New research explores a potential link between Epstein-Barr virus and primary sclerosing cholangitis.

Major Milestone Reached in PSC Cancer Risk Study

02 Feb 2026

100 samples collected: DNA methylation study advances early cancer detection in PSC.

Progress Update: Characterising Genetic Changes in Bile Ducts

30 Jan 2026

PSC research on genetic changes in bile ducts is now in its key analytical phase to unlock understanding.

Molecular Signatures Identified to Predict Primary Sclerosing Cholangitis Progression and Cancer Risk

28 Jan 2026

New blood-based markers could help predict primary sclerosing cholangitis progression and cancer risk.

PSC-IBD Bowel Cancer Risk Study Shows Promising Findings

26 Jan 2026

New PSC-IBD research from Dr Chandni Radia suggests bowel cancer risk may be lower than previously thought, helping us build evidence to tailor future colonoscopy guidelines.

Promising Leap Forward in Research on PSC and Bile Duct Cancer

23 Jan 2026

New research identifies a marker (COX2) linking lab models to real-world PSC patients, advancing early cancer detection efforts.

Major Progress in Developing Simple Blood Test for Earlier Bile Duct Cancer Detection in PSC

21 Jan 2026

Major Progress in Developing Simple Blood Test for Earlier Bile Duct Cancer Detection in PSC

Research Update: New Clues to PSC Progression

19 Jan 2026

Dr Anthony George shares new insights into immune cells and predicting PSC progression.

New PSC Support Research Uncovers Critical Link Between Liver and Small Intestine

18 Jan 2026

PSC Support funding helps uncover new clues in the small intestine for potential new treatments for primary sclerosing cholangitis.

PSC Treatment Breakthroughs 2025

08 Jan 2026

Discover the 2025 breakthroughs in PSC research and how they are shaping 2026.

Nov 2025 Research Roundup

30 Nov 2025

Our November roundup features encouraging Phase II trial updates, new gut-liver research, and UK policy changes to speed up rare disease treatment access.

ELMWOOD Clinical Trial Update

14 Nov 2025

Latest results shared at international liver conference.

SPRING Clinical Trial Update

14 Nov 2025

Latest results shared at international liver conference.

Time to Talk About Bile Duct Cancer Risk in PSC

13 Nov 2025

Patient survey results shared at major liver conference.

Oct 2025 Research Roundup

31 Oct 2025

A look at our recent visit to Belfast for the BASL conference and Information Day

Sep 2025 Research Roundup

30 Sep 2025

Read about our latest research activities.

July 2025 Research Roundup

31 Jul 2025

Read the latest updates on the SPRING trial, the NHS 10 Year Health Plan, how we are funding research this year and how PSC Support is influencing real change in research and policy.

May 2025 Research Roundup

31 May 2025

Research Roundup May 2025 Links Learning from PBC Bile Duct Cancer Conference Research YOU’VE funded International Liver Research Conference (with major PSC announcements) Watch Ask the Expert with Dr Trivedi Learning from PBC This month, I attended a meeting of PBC experts in Amsterdam who want to understand what evidence is required to show that…

Clinical Trial for Elafibranor

11 May 2025

Encouraging results from the ELMWOOD clinical trial.

Clinical Trial for Norucholic Acid – Latest Results

11 May 2025

Positive results from the Phase 3 NUC-5 clinical trial.

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