PSC Support was set up over twenty years ago. Supporting and funding research has always been an important part of our work, thanks to your generous donations. We are proud of our grant research programme, which has clearly defined and transparent mechanisms in place, and a robust peer-review process to ensure your donations fund only the highest quality, most worthwhile PSC research. However, we must do more to accelerate this progress. By 2030, we will fund and support more PSC research than ever before, offering over £1 million in grants to researchers as part of our commitment to help find effective treatments for everyone with PSC by 2030.
Studies funded by PSC Support:
Dr Anthony George
2024
Uncovering the processes that drive inflammation and damage in PSC.
Dr Nicholas Ilott
2024
Assessing protein levels in the small intestine in people with PSC and ulcerative colitis to understand how the liver and the intestine interact with each other in PSC.
Ryan James
2024
Developing a tool to measure quality of life in people with PSC (Stage 2)
Professor Jesús Bañales and Dr Pedro Rodrigues
2023
Continuing to develop a blood test to detect early bile duct cancer and to predict who is most at risk in people with PSC.
Dr Simon Rushbrook
2023
Continuing to develop a blood test to diagnose PSC. His previous research, funded by PSC Support, found ten promising antibody markers which he will now test on a larger scale to find one that is unique to PSC.
Dr Edward Jarman
2023
Investigating how the cells in people with PSC can develop into bile duct cancer (cholangiocarcinoma).
Dr Palak Trivedi
2021
Investigating the potential of a new treatment (faecal microbiota transplantation) to slow the progression of PSC and improve the quality of life for patients.
Dr Simon Rushbrook and Dr Liz Goode
2019
Developing a diagnostic blood test for people with PSC.
Professor Jesús Bańales
2019
Investigating non-invasive biomarkers in blood to predict PSC prognosis and early cholangiocarcinoma (CCA) development.
Dr Veronica Ranieri
2018
Creating a personalised psychological intervention for primary sclerosing cholangitis: understanding mental health and wellbeing among people with PSC.
Dr Elena Marcus
2018
Developing a tool to measure quality of life in people with PSC.
Dr Kate Lynch
2018
Characterising the subtypes and function of liver immune cells in PSC/UC.
Dr Palak Trivedi
2017
The VAPoR Study: Validating the Prognostic Utility of Vascular Adhesion Protein 1 in PSC.
Dr Elizabeth Goode
2017
Identifying the true genes underlying each of the twenty-three known loci associated with risk of developing PSC.
Professor Catherine WIlliamson
2016
Investigating the effect of male cholestasis (i.e. men with PSC) on the epigenome of sperm and the impact on the health of children of men with cholestasis.
Dr Rachel Guest
2016
Developing an unbiased screen for novel clinical and molecular biomarkers of the progression of primary sclerosing cholangitis to biliary tract cancer
Professor Gideon Hirschfield
2015
Developing the West Midlands Virtual PSC Programme
Professor Luke Boulter
2015
Investigating the role of non-canonical Wnt signalling in the establishment of fibrosis during PSC
UK-PSC
2014
UK-PSC Project Manager
