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PSC Research Explained

Summaries of PSC research

PSC Research Explained by PSC Support

Stay informed with PSC Research Explained. We translate the latest clinical trials and scientific breakthroughs into clear, plain English summaries for patients:

Sep 2025 Research Roundup

30 Sep 2025

Read about our latest research activities.

July 2025 Research Roundup

31 Jul 2025

Read the latest updates on the SPRING trial, the NHS 10 Year Health Plan, how we are funding research this year and how PSC Support is influencing real change in research and policy.

May 2025 Research Roundup

31 May 2025

Research Roundup May 2025 Links Learning from PBC Bile Duct Cancer Conference Research YOU’VE funded International Liver Research Conference (with major PSC announcements) Watch Ask the Expert with Dr Trivedi Learning from PBC This month, I attended a meeting of PBC experts in Amsterdam who want to understand what evidence is required to show that…

Clinical Trial for Elafibranor

11 May 2025

Encouraging results from the ELMWOOD clinical trial.

Clinical Trial for Norucholic Acid – Latest Results

11 May 2025

Positive results from the Phase 3 NUC-5 clinical trial.

Blood Test to Detect Bile Duct Cancer

10 May 2025

New “3-in1” test for PSC and bile duct cancer.

Aspirin and Cancer Update

29 Mar 2025

Can aspirin stop the spread of cancer? Latest update.

New Phase 3 Trial Planned for Nebokitug in PSC

20 Feb 2025

A new trial is planned for PSC

Positive Results Announced from SPRING Trial

25 Jul 2024

Positive results from the SPRING Clinical Trial announced today

More Encouraging Data from the INTEGRIS Clinical Trial

15 Jul 2024

Pliant Therapeutics announce latest results from the INTEGRIS Clinical Trial

More Mission 2030 Research Announced

09 Jul 2024

PSC Support has awarded £52,500 to Dr Anthony George to uncover the processes that drive inflammation and damage in PSC.

A Step Closer to a PSC Blood Test

13 Mar 2023

Update from Dr Rushbrook and Dr Goode

Study to Investigate Brodalumab in the Treatment of PSC

31 Jan 2023

Study to Investigate Brodalumab in the Treatment of Primary Sclerosing Cholangitis

New European Guidelines for the care of People with PSC

30 Nov 2022

A summary of the latest PSC care guidelines for Europe.

Itch Survey Results

28 Jun 2022

Results of the PSC multinational itch survey

Care of Patients With Liver Disease During the COVID-19 Pandemic – UPDATE

03 Feb 2021

European experts have made recommendations on the care of liver disease during the COVID-19 pandemic.

Spotlight on Colonoscopies

30 Jan 2021

Update on preparing for your next colonoscopy with some new tips from patients.

Research Report on PSC from EASL International Liver Congress

12 Nov 2020

Our Report on PSC research from the International Liver Congress 2020

Bile Acid Pathways in PSC-IBD

09 Oct 2020

Are the mechanisms that drive inflammation in the bowel in people with PSC different to that seen in people with UC alone? Dr Nabil Quraishi

Effects of PSC on Risks of Cancer in People with IBD

30 Sep 2020

A new study has looked at the health records of people with IBD to understand what happens to them if they develop PSC.

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